相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Cancer Statistics, 2014
Rebecca Siegel et al.
CA-A CANCER JOURNAL FOR CLINICIANS (2014)
FAK Inhibition Abrogates the Malignant Phenotype in Aggressive Pediatric Renal Tumors
Michael L. Megison et al.
MOLECULAR CANCER RESEARCH (2014)
Gene Expression Profiling Identifies Important Genes Affected by R2 Compound Disrupting FAK and P53 Complex
Vita M. Golubovskaya et al.
CANCERS (2014)
The Role of Focal Adhesion Kinase in Lung Cancer
Grace K. Dy
Anti-Cancer Agents in Medicinal Chemistry (2013)
Inhibiting the Interaction of cMET and IGF-1R with FAK Effectively Reduces Growth of Pancreatic Cancer Cells in vitro and in vivo
Deniz A. Ucar et al.
Anti-Cancer Agents in Medicinal Chemistry (2013)
Sonic hedgehog signaling pathway induces cell migration and invasion through focal adhesion kinase/AKT signaling-mediated activation of matrix metalloproteinase (MMP)-2 and MMP-9 in liver cancer
Jing-Song Chen et al.
CARCINOGENESIS (2013)
Disrupting the Scaffold to Improve Focal Adhesion Kinase-Targeted Cancer Therapeutics
William G. Cance et al.
SCIENCE SIGNALING (2013)
The FAK scaffold inhibitor C4 disrupts FAK-VEGFR-3 signaling and inhibits pancreatic cancer growth
Elena Kurenova et al.
ONCOTARGET (2013)
Vitamin D3 triggers antitumor activity through targeting hedgehog signaling in human renal cell carcinoma
Valerian Dormoy et al.
CARCINOGENESIS (2012)
A small molecule focal adhesion kinase (FAK) inhibitor, targeting Y397 site: 1-(2-hydroxyethyl)-3, 5, 7-triaza-1-azoniatricyclo [3.3.1.13,7]decane; bromide effectively inhibits FAK autophosphorylation activity and decreases cancer cell viability, clonogenicity and tumor growth in vivo
Vita M. Golubovskaya et al.
CARCINOGENESIS (2012)
Focal adhesion kinase and its signaling pathways in cell migration and angiogenesis
Xiaofeng Zhao et al.
ADVANCED DRUG DELIVERY REVIEWS (2011)
Akt directly regulates focal adhesion kinase through association and serine phosphorylation: implication for pressure-induced colon cancer metastasis
Shouye Wang et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2011)
Anoikis Disruption of Focal Adhesion-Akt Signaling Impairs Renal Cell Carcinoma
Shinichi Sakamoto et al.
EUROPEAN UROLOGY (2011)
Inhibition of Focal Adhesion Kinase by PF-562,271 Inhibits the Growth and Metastasis of Pancreatic Cancer Concomitant with Altering the Tumor Microenvironment
Jayme B. Stokes et al.
MOLECULAR CANCER THERAPEUTICS (2011)
LIM-class homeobox gene Lim1, a novel oncogene in human renal cell carcinoma
V. Dormoy et al.
ONCOGENE (2011)
Role of the RNA-binding protein HuR in human renal cell carcinoma
Sabrina Danilin et al.
CARCINOGENESIS (2010)
FAK is involved in invasion and metastasis of hepatocellular carcinoma
Jing-Song Chen et al.
CLINICAL & EXPERIMENTAL METASTASIS (2010)
Therapeutic potential and limitations of new FAK inhibitors in the treatment of cancer
Alexander Schultze et al.
EXPERT OPINION ON INVESTIGATIONAL DRUGS (2010)
Pyk2 Inhibition of p53 as an Adaptive and Intrinsic Mechanism Facilitating Cell Proliferation and Survival
Ssang-Taek Lim et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Role of kinase-independent and -dependent functions of FAK in endothelial cell survival and barrier function during embryonic development
Xiaofeng Zhao et al.
JOURNAL OF CELL BIOLOGY (2010)
Overexpression of DLC-1 induces cell apoptosis and proliferation inhibition in the renal cell carcinoma
Tao Zhang et al.
CANCER LETTERS (2009)
Autophosphorylation-independent and -dependent Functions of Focal Adhesion Kinase during Development
Jean-Marc Corsi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Targeting Renal Cell Carcinoma
Robert J. Motzer et al.
JOURNAL OF CLINICAL ONCOLOGY (2009)
The sonic hedgehog signaling pathway is reactivated in human renal cell carcinoma and plays orchestral role in tumor growth
Valerian Dormoy et al.
MOLECULAR CANCER (2009)
Neurofibromin Physically Interacts With the N-Terminal Domain of Focal Adhesion Kinase
Frederick Kweh et al.
MOLECULAR CARCINOGENESIS (2009)
The role of focal adhesion kinase in tumor initiation and progression
Paolo P. Provenzano et al.
CELL ADHESION & MIGRATION (2009)
Signaling inhibitors in metastatic renal cell carcinoma
Bernard Escudier
CANCER JOURNAL (2008)
A Small Molecule Inhibitor, 1,2,4,5-Benzenetetraamine Tetrahydrochloride, Targeting the Y397 Site of Focal Adhesion Kinase Decreases Tumor Growth
Vita M. Golubovskaya et al.
JOURNAL OF MEDICINAL CHEMISTRY (2008)
Nuclear FAK promotes cell proliferation and survival through FERM-enhanced p53 degradation
Ssang-Taek Lim et al.
MOLECULAR CELL (2008)
Cancer incidence and mortality in France over the period 1980-2005
A. Belot et al.
REVUE D EPIDEMIOLOGIE ET DE SANTE PUBLIQUE (2008)
Targeting the nuclear factor-κB rescue pathway has promising future in human renal cell carcinoma therapy
Carole Sourbier et al.
CANCER RESEARCH (2007)
Cellular characterization of a novel focal adhesion kinase inhibitor
Jill K. Slack-Davis et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Polyethylenimine-complexed plasmid particles targeting focal adhesion kinase function as melanoma tumor therapeutics
Shufeng Li et al.
MOLECULAR THERAPY (2007)
Focal adhesion kinase targeting using in vivo short interfering RNA delivery in neutral liposomes for ovarian carcinoma therapy
Jyotsnabaran Halder et al.
CLINICAL CANCER RESEARCH (2006)
Organization and post-transcriptional processing of focal adhesion kinase gene
Jean-Marc Corsi et al.
BMC GENOMICS (2006)
Role of hypoxia-inducible factor (HIF)-1α-versus HIF-2α in the regulation of HIF target genes in response to hypoxia, insulin-like growth factor-1, or loss of von Hippel-Lindau function:: Implications for targeting the HIF pathway
Veronica A. Carroll et al.
CANCER RESEARCH (2006)
The phosphoinositide 3-kinase/Akt pathway: A new target in human renal cell carcinoma therapy
Carole Sourbier et al.
CANCER RESEARCH (2006)
The role of focal-adhesion kinase in cancer. A ew therapeutic opportunity
GW McLean et al.
NATURE REVIEWS CANCER (2005)
P27Kip and cyclin D1 are necessary for focal adhesion kinase regulation of cell cycle progression in glioblastoma cells propagated in vitro and in vivo in the scid mouse brain
Q Ding et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Focal adhesion kinase suppresses apoptosis by binding to the death domain of receptor-interacting protein
E Kurenova et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
Focal adhesion kinase regulation of N-WASP subcellular localization and function
XY Wu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Parathyroid hormone-related protein is an essential growth factor for human clear cell renal carcinoma and a target for the von Hippel-Lindau tumor suppressor gene
T Massfelder et al.
CANCER RESEARCH (2004)
A decade of tyrosine kinases: from gene discovery to therapeutics
RJ Craven et al.
SURGICAL ONCOLOGY-OXFORD (2003)
Identification of transcription factor KLF8 as a downstream target of focal adhesion kinase in its regulation of cyclin D1 and cell cycle progression
JH Zhao et al.
MOLECULAR CELL (2003)
Role of Grb7 targeting to focal contacts and its phosphorylation by focal adhesion kinase in regulation of cell migration
DC Han et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
分享论文
