期刊
AKTUELLE NEUROLOGIE
卷 45, 期 8, 页码 605-616出版社
GEORG THIEME VERLAG KG
DOI: 10.1055/a-0649-0724
关键词
amyloidosis; transthyretin; polyneuropathy; heart; therapy
Transthyretin amyloidosis (ATTR amyloidosis) is a rare and rapidly progressive disease caused by mutations within the transthyretin gene. Because of its rarity, the disease is little-known with the result of a frequently missed diagnosis and, therefore, appropriate therapy often being delayed. Liver transplantation has become a treatment option since the mid 90 s. In 2011, an oral drug stabilizing transthyretin and, subsequently, stopping amyloid production has been introduced. Additional substances are currently being studied, some of which are awaiting approval. The present paper written by German speaking experts gives recommendations for diagnosis, management and therapy of ATTR amyloidosis and is intended to increase awareness for this hereditary but treatable disease within the medical community.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据