期刊
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
卷 77, 期 -, 页码 24-35出版社
ELSEVIER
DOI: 10.1016/j.ijbiomac.2015.02.050
关键词
Biological macromolecules; Marine organisms; Wound healing; Skin tissue engineering
资金
- Basic Science Research Program through the National Research Foundation of Korea (NRF) - Ministry of Education, Science, and Technology [2013R1A1A1A05013577]
- Marine Technology Application Program of Ministry of Oceans and Fisheries, Republic of Korea [PJT200673]
- National Research Foundation of Korea [2013R1A1A1A05013577] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
Wound healing is a complex biological process that depends on the wound condition, the patient's health, and the physicochemical support given through external materials. The development of bioactive molecules and engineered tissue substitutes to provide physiochemical support to enhance the wound healing process plays a key role in advancing wound-care management. Thus, identification of ideal molecules in wound treatment is still in progress. The discovery of natural products that contain ideal molecules for skin tissue regeneration has been greatly advanced by exploration of the marine bioenvironment. Consequently, tremendously diverse marine organisms have become a great source of numerous biological macromolecules that can be used to develop tissue-engineered substitutes with wound healing properties. This review summarizes the wound healing process, the properties of macromolecules from marine organisms, and the involvement of these molecules in skin tissue regeneration applications. (C) 2015 Elsevier B.V. All rights reserved.
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