Absence of Detectable Replication of Human Bocavirus Species 2 in Respiratory Tract

Human bocavirus (HBoV) commonly infects young children and is associated with respiratory disease; disease associations,of the divergent HBoV-2 species are unknown. Frequent HBoV-2 detection in fecal samples indicated widespread circulation in the United Kingdom and Thailand, but its lack of detection among 6,524 respiratory samples indicates likely differences from HBoV-1 in tropism/pathogenesis.