期刊
AGE AND AGEING
卷 43, 期 4, 页码 542-547出版社
OXFORD UNIV PRESS
DOI: 10.1093/ageing/aft208
关键词
anxiety; stroke; cohort studies; incidence; prevalence; older people
资金
- Guy's and St Thomas' Hospital Charity
- Stroke Association
- Department of Health HQIP grant, UK
- National Institute for Health Research Programme [RP-PG-0407-10184]
- Department of Health via the National Institute for Health Research (NIHR) Biomedical Research Centre
- King's College London
- National Institute for Health Research (NIHR) under its Programme Grants for Applied Research funding scheme [RP-PG-0407-10184]
- National Institutes of Health Research (NIHR) [RP-PG-0407-10184] Funding Source: National Institutes of Health Research (NIHR)
- National Institute for Health Research [CL-2012-19-004, NF-SI-0510-10060, RP-PG-0407-10184] Funding Source: researchfish
Methods: data from the South London Stroke Register (1995-2010). Patients were assessed at the time of the stroke, at 3 months, 1 year and then annually for up to 10 years. Baseline data included socio-demographics and stroke severity. Follow-up data included assessments for anxiety and depression (hospital anxiety and depression scale), disability, cognition and QoL. Multivariate regression was used to investigate predictors and associated outcomes of anxiety. Results: incidence of anxiety up to 10 years ranged from 17 to 24%. Cumulative incidence: 57%. Prevalence range: 32-38%. Amongst patients with anxiety, 58% were anxious at 3 months. 57-73% of patients with anxiety had co-morbid depression. Predictors of anxiety included age under 65, female gender, inability to work, depression treatment, smoking and stroke severity. Anxiety at 3 months was associated with lower QoL at follow-up. Conclusions: anxiety is a frequent problem affecting stroke survivors in the long term. Clinicians should pay attention to patients at risk of anxiety since it is associated with lower QoL and depression.
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