期刊
AGE AND AGEING
卷 41, 期 5, 页码 677-681出版社
OXFORD UNIV PRESS
DOI: 10.1093/ageing/afs087
关键词
fat mass; fat distribution; lean mass; mortality; dual-energy X-ray absorptiometry (DXA); older people
资金
- Visare Norr
- Swedish Society of Medicine
Objective: to investigate associations between different aspects of body composition and mortality in older people. Methods: the study population comprised 921 participants aged >= 65 years who underwent dual-energy X-ray (DXA) absorptiometric examination at the Sports Medicine Unit, Umea University. The main reason for admission was clinical suspicion of osteoporosis. Total, abdominal and gynoid fat masses and lean body mass were measured by DXA absorptiometry at baseline, and the cohort was followed (mean duration, 9.2 years) for mortality events. Results: during follow-up, 397 participants died. Lean mass was associated negatively with mortality in men and women (P < 0.001). Total fat mass showed a U-shaped association with mortality in men (P < 0.01) and a negative association in women (P < 0.01). A higher ratio of abdominal to gynoid fat mass increased mortality risk in women (P = 0.04), but not in men (P = 0.91). Conclusions: lean mass is associated strongly with survival in older subjects. Greater fat mass is protective in older women, whereas very low or very high fat mass increases the risk of death in men. Further research is needed to better understand the mechanisms underlying these associations.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据