期刊
AGE AND AGEING
卷 39, 期 3, 页码 331-337出版社
OXFORD UNIV PRESS
DOI: 10.1093/ageing/afq022
关键词
disability; elderly; handgrip strength; health; sarcopenia
资金
- Netherlands Organisation of Scientific Research (ZonMw)
- Ministry of Health, Welfare and Sports
- Netherlands Genomics Initiative/Netherlands Organization for scientific research
- Netherlands Consortium for Healthy Aging [05040202, 050-060-810 NCHA]
Objective: this study aimed to assess if handgrip strength predicts changes in functional, psychological and social health among oldest old. Design: the Leiden 85-plus Study is a prospective population-based follow-up study. Subjects: five-hundred fifty-five, all aged 85 years at baseline, participated in the study. Methods: handgrip strength was measured with a handgrip strength dynamometer. Functional, psychological and social health were assessed annually. Baseline data on chronic diseases were obtained from the treating physician, pharmacist, electrocardiogram and blood sample analysis. Results: at age 85, lower handgrip strength was correlated with poorer scores in functional, psychological and social health domains (all, P < 0.001). Lower baseline handgrip strength predicted an accelerated decline in activities of daily living (ADL) and cognition (both, P < 0.001), but not in social health (P > 0.30). Conclusion: poor handgrip strength predicts accelerated dependency in ADL and cognitive decline in oldest old. Measuring handgrip strength could be a useful instrument in geriatric practice to identify those oldest old patients at risk for this accelerated decline.
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