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P. Sebastiani et al.
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Felipe Sierra et al.
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Sekar Kathiresan et al.
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Kelly A. Frazer et al.
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Robert Plomin et al.
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Oscar H. Franco et al.
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Friederike Flachsbart et al.
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Eric L. Greer et al.
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Teri A. Manolio et al.
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D. Craig Willcox et al.
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Bradley J. Wilicox et al.
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Shaun Purcell et al.
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Aviv Bergman et al.
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Kwang-Il Goh et al.
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Petko M. Petkov et al.
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Joel H. Graber et al.
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The plasticity of aging: Insights from long-lived mutants
C Kenyon
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Unique lipoprotein phenotype and genotype associated with exceptional longevity
N Barzilai et al.
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Ratchets and clocks: The cell cycle, ubiquitylation and protein turnover
SI Reed
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AK Roy et al.
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G De Benedictis et al.
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The network and the remodeling theories of aging:: historical background and new perspectives
C Franceschi et al.
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Mitotic misregulation and human aging
DH Ly et al.
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