4.2 Article

Chronic Kidney Disease and End-Stage Renal Disease in the Elderly Population: Current Prevalence, Future Projections, and Clinical Significance

期刊

ADVANCES IN CHRONIC KIDNEY DISEASE
卷 17, 期 4, 页码 293-301

出版社

W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1053/j.ackd.2010.03.010

关键词

Chronic kidney disease; Elderly; Glomerular filtration rate; Albuminuria; Cardiovascular disease

资金

  1. NIDDK NIH HHS [K23 DK081017-04, K23 DK081017] Funding Source: Medline

向作者/读者索取更多资源

The world's population is aging, with the number of older adults projected to increase dramatically over the next 2 decades. This trend poses major challenges to health care systems, reflecting the greater health care use and more comorbid conditions among elderly adults. Chronic kidney disease (CKD) is a substantial concern in the elderly population, with both an increasing incidence of treated kidney failure with dialysis as well as a high prevalence of earlier stages of CKD. Given the high burden of risk factors for CKD, the high prevalence of CKD in the elderly population is not surprising, with the rise in obesity, diabetes, and hypertension in middle-aged adults likely foreshadowing further increases in CKD prevalence among the elderly population. It is now commonly agreed that the presence of CKD identifies a higher risk state in the elderly population, with increased risk for multiple adverse outcomes, including kidney failure, cardiovascular disease, cognitive impairment, and death. Accordingly, CKD in older adults is worthy of attention by both health care providers and patients, with the presence of a reduced glomerular filtration rate or albuminuria in the elderly potentially informing therapeutic and diagnostic decisions for these individuals. (C) 2010 by the National Kidney Foundation, Inc. All rights reserved.

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