N-Imide Ylide-Based Reactions: C-H Functionalization, Nucleophilic Addition and Cycloaddition

As valuable building blocks for introducing nitrogen, N-imide ylides represent an important class of reactive species and are synthons for the synthesis of nitrogen-containing heterocycles that potentially have biological activities. During the past decades, tremendous efforts have been devoted to the tandem processes involving N-imide ylides as well as their asymmetric applications. In particular, several types of N-imide ylide-based reactions have been established, such as C-H functionalization, nucleophilic addition, and cycloaddition, etc. In this review, recent advances in N-imide ylides chemistry are presented ordered according to the sequence of various reaction types.