期刊
ADVANCED SYNTHESIS & CATALYSIS
卷 356, 期 9, 页码 2081-2087出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/adsc.201301182
关键词
carbene ligands; heterogeneous catalysis; high throughput screening; homogeneous catalysis; metathesis
资金
- European Research Council (ERC) [StG 258740]
An improved immobilised Grubbs 2nd generation catalyst and its application in flow-through devices, shown for on-column reaction gas chromatography (ocRGC), has been studied. The coupling of a reaction capillary and a separation column in GC/MS allows direct reaction monitoring and analysis of conversion as well as reaction kinetics. The presented permanently bonded N-heterocyclic carbene ligand shows a great stability and activity in ring closing metathesis reactions. A salt-free approach was used to generate the carbene ligand, which can be directly monitored by mass spectrometry. The very flexible design of the immobilised ligand system in reaction channels and capillaries of flow through systems allows the preparation of various catalysts using a broad variety of metal precursors. This strategy of immobilised catalytically active complexes offers a wide range of on-column reactions combinable with fast reaction screening by high throughput experimentation.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据