期刊
ADVANCED SYNTHESIS & CATALYSIS
卷 355, 期 6, 页码 1023-1052出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/adsc.201200808
关键词
asymmetric catalysis; organocatalysis; spiro-oxindoles; stereoselectivity
资金
- NSFC [20932003, 91213302, 21272102, 21202071]
- National S&T Major Project of China [2012ZX09504001-003]
The asymmetric organocatalysis is definitely one of the most powerful and versatile tools for the rapid construction of various spirocyclic oxindoles. In the past few years, a number of successful strategies based on organocatalysis have been developed for the construction of 3,3-spirocyclic oxindoles in high yields and excellent enantioselectivities under mild conditions. In this review, recent advances in this area are summarized and classified according to the spiro ring fused at the 3-position of the oxindole core.
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