期刊
ADVANCED SYNTHESIS & CATALYSIS
卷 355, 期 8, 页码 1495-1499出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/adsc.201300189
关键词
amination; aryl halides; copper; nitriles
资金
- National Natural Science Foundation of China [21202109, 21072140]
- Sichuan Provincial Department of Education [11ZA108]
- Sichuan Normal University [DJ2012-07]
- Sichuan Province Higher Education System Key Laboratory of Advanced Functional Materials [KFKT2013-02]
- Sichuan Normal University
A copper-catalyzed amination of aryl halides with nitriles has been developed. The use of nitriles as nitrogen nucleophiles can make the synthesis of N-arylamides more simple than that using amides through in-situ hydrolysis. A variety of N-arylamides and benzoxazole derivatives can be synthesized according to this approach.
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