4.7 Article

A Copper(II) Triflate-Catalyzed Tandem Friedel-Crafts Alkylation/Cyclization Process towards Dihydroindenes

期刊

ADVANCED SYNTHESIS & CATALYSIS
卷 353, 期 7, 页码 1055-1060

出版社

WILEY-V C H VERLAG GMBH
DOI: 10.1002/adsc.201000966

关键词

dihydroindenes; Friedel-Crafts alkylation; homogeneous catalysis; tandem reactions

资金

  1. Institute of Bioengineering and Nanotechnology (Biomedical Research Council, Agency for Science, Technology and Research, Singapore)

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A one-pot synthesis of dihydroindenes from substituted benzenes and haloalkenes was developed. The reaction proceeded via a copper(II) triflate [Cu(OTf)(2)]-catalyzed tandem Friedel-Crafts alkylation/cyclization process with high efficiency under relatively mild conditions.

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