One-Pot Ring-Closing Metathesis (RCM)/Oxidation by an Assisted Tandem Ruthenium Catalysis for the Synthesis of 2-Quinolones

We have developed a one-pot ring-closing metathesis (RCM)/oxidation methodology to yield various 2-quinolines from 2-vinyl-N-allylaniline derivatives. This is a first example of an oxidation involving methylene (CH2) groups with modified Grubbs-type ruthenium complexes. Hence, this adds an example of a non-methathesis reaction using a ruthenium carbene catalyst.