期刊
ADVANCED SYNTHESIS & CATALYSIS
卷 352, 期 2-3, 页码 347-350出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/adsc.200900706
关键词
arylation; benzimidazoles; cascade reactions; copper catalysts; multicomponent reactions
资金
- National Natural Science Foundation of China [20872128]
- Scientific Research Fund of Educational Bureau of Zhejiang Province [20070304]
A copper-catalyzed one-pot synthesis of functionalized benzimidazoles has been developed. The procedure combines the copper-catalyzed three-component cascade reaction of sulfonyl azides, alkynes and 2-bromoaniline and the copper-catalyzed intramolecular N-arylation of sulfon-amides in one sequence, which afforded the products in moderate to good yields.
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