Bromodimethylsulfonium bromide-silver triflate: A new powerful promoter system for the activation of thioglycosides

Bromodimethylsulfonium bromide (BDMS) in combination with silver triflate provides a very efficient thiophilic promoter system, capable of activating both disarmed and armed thioglycosides for glycosidic bond formation. The usefulness of this new promoter is illustrated by a successful reactivity-based one-pot oligosaccharide assembly.