期刊
INTERNAL MEDICINE
卷 54, 期 10, 页码 1227-1230出版社
JAPAN SOC INTERNAL MEDICINE
DOI: 10.2169/internalmedicine.54.3511
关键词
hypereosinophilic syndrome; acute eosinophilic myocarditis; isoniazid
It has been reported that hypereosinophilic syndrome may be induced by antituberculosis drugs. We herein report the case of a 43-year-old man who had been on antituberculosis drugs for two months to treat tuberculous meningitis. During therapy, he suffered from drug rash with eosinophilia and systemic symptoms (DRESS) presenting as acute eosinophilic myocarditis, as confirmed on a histopathologic examination. According to the patient's medication history, clinical features and accessory examination findings, the eosinophilic myocarditis was thought to be possibly induced by isoniazid. Although further investigations are needed to confirm causality, isoniazid may be added to the list of drugs with the potential to cause DRESS syndrome.
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