4.8 Article

Switchable Water-Adhesive, Superhydrophobic Palladium-Layered Silicon Nanowires Potentiate the Angiogenic Efficacy of Human Stem Cell Spheroids

期刊

ADVANCED MATERIALS
卷 26, 期 41, 页码 7043-+

出版社

WILEY-V C H VERLAG GMBH
DOI: 10.1002/adma.201402273

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资金

  1. Priority Research Centers Program through the National Research Foundation (NRF) of Korea - Ministry of Education, Science and Technology (MEST) [2012-0006689]
  2. NRF - Ministry of Science, ICT, and Future Planning (MSIP), Republic of Korea [2010-0020409]
  3. Translational Research Center for Protein Function Control (TRCP) - MSIP, Republic of Korea [2009-0083522]
  4. Industrial strategic technology development program - Ministry of Knowledge Economy (MKE, Korea) [10041041]
  5. NRF - Korean government (MEST) [2011-0028594]
  6. Korea Evaluation Institute of Industrial Technology (KEIT) [10041041] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
  7. National Research Foundation of Korea [2013H1A8A1004238, 2010-0020409, 2009-0093823, 2009-0083522] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)

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A switchable water-adhesive, super-hydrophobic nanowire surface is developed for the formation of functional stem cell spheroids. The sizes of hADSC spheroids are readily controllable on the surface. Our surface increases cell-cell and cell-matrix interaction, which improves viability and paracrine secretion of the spheroids. Accordingly, the hADSC spheroids produced on the surface exhibit significantly enhanced angiogenic efficacy.

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