4.8 Article

Combined Detection of Cancer Cells and a Tumor Biomarker using an Immunomagnetic Sensor for the Improvement of Prostate-Cancer Diagnosis

期刊

ADVANCED MATERIALS
卷 26, 期 22, 页码 3662-3666

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WILEY-V C H VERLAG GMBH
DOI: 10.1002/adma.201305842

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  1. National Science Council of the Republic of China
  2. Industrial Technology Research Institute
  3. National Tsing Hua University
  4. Chang Gung Memorial Hospital [NSC102-2622-E-007-024-CC3, NSC101-2221-E-182-011-MY3, 102N2024E1, 102N2772E1, 102A0050J2, CMRPG3B1601, CMRPG3B1602]

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Capture and detection of both a relevant antigen and cancer cells are demonstrated using magnetic graphene oxide (MGO) possessing conjugated antibodies. By simply dropping the MGO onto the surface of Pt electrodes while in a magnetic field, the sensor is rapidly constructed. The dual approach of the sensor potentially offers a more accurate, rapid platform than current tests based on immunological methods.

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