期刊
ADVANCED MATERIALS
卷 25, 期 4, 页码 545-551出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/adma.201202851
关键词
biomedical applications; poly(L-lactic acid); nanosheets; patchwork; burn therapy
类别
资金
- High-Tech Research Center Project at Waseda University
- JSPS [21300181]
- National Defense Medical College
- Grants-in-Aid for Scientific Research [21300181] Funding Source: KAKEN
Freestanding poly(L-lactic acid) (PLLA) nanosheets are mass-produced by a simple combination of a spin-coating-assisted multi-layering process and a peeling technique. The resulting PLLA nanosheets are fragmented by homogenization and then reconstructed into a patchwork sheet on various surfaces without any adhesive reagents. The patchwork is shown to offer excellent protection against burn wound infection with Pseudomonas aeruginosa, and may therefore be an alternative to conventional burn therapy for prevention of infection.
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