期刊
ADVANCED MATERIALS
卷 22, 期 21, 页码 2343-2348出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/adma.200904442
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- Kodak Ltd
- Institut Carnot (France)
Chemical nanosensors with a submicrometer core-shell composite design, based on a polymer core, a molecularly imprinted polymer (MIP) shell for specific analyte recognition, and an interlayer of gold nanoparticles for signal amplification, are described. SERS measurements on single nanosensors yield detection limits of 10(-7) M for the beta-blocker propranolol, several orders of magnitude lower than on plain MIP spheres.
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