期刊
ADVANCED MATERIALS
卷 22, 期 8, 页码 880-+出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/adma.200902895
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资金
- National Cancer Institute of the National Institutes of Health [U54 CA 119335, 5-R01-CA124427, U54 CA119349]
- Moores UCSD Cancer Center
- UCSD NanoTUMOR Center
A cooperative nanosystem consisting of two distinct nanomaterials works in vivo to detect tumor tissues and deliver drugs to the site. Gold nanorods (GNRs) localize to the tumor region, where they report their location and convert near-infrared radiation to thermal energy. Circulating thermally labile therapeutic liposomes respond to the thermal signal, releasing their drug payload selectively in the GNR-populated tumor.
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