4.8 Article

Encapsulation of Water-Insoluble Drugs in Polymer Capsules Prepared Using Mesoporous Silica Templates for Intracellular Drug Delivery

期刊

ADVANCED MATERIALS
卷 22, 期 38, 页码 4293-+

出版社

WILEY-V C H VERLAG GMBH
DOI: 10.1002/adma.201001497

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  1. Australian Research Council
  2. National Health and Medical Research Council (NHMRC) [433613, 487922]
  3. China Scholarship Council for a joint-Education PhD Program Scholarship

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Water-insoluble compounds were encapsulated in polymer capsules through mesoporous silica nanoparticle-mediated layer-by-layer assembly. The drug-loaded capsules exhibit excellent colloidal stability and high potency to colorectal cancer cells in vitro with similar cytotoxicity to the free drug dissolved in organic solvent.

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