期刊
ADVANCED MATERIALS
卷 23, 期 6, 页码 787-+出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/adma.201003763
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资金
- French National Research Agency [ANR-06-PCV-027]
- European project Magnifyco [NMP4-SL-2009-228622]
Alginate microbeads with iron oxide nanoparticle heaters that carry doxorubicin are investigated in vitro for simultaneous drug targeting and local heat generation (hyperthermia). Application of an alternative magnetic field (AMF) causes magnetic-hyperthermia-enhanced doxorubicin release. The AMF-triggered drug release and hyperthermia exhibit synergistic effects and result in significant tumor cell death.
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