Core-Sheath Nanofibers Containing Colloidal Arrays in the Core for Programmable Multi-Agent Delivery

Polymeric core-sheath nanofibers consisting of polymeric sheath and arrays of colloids in the core are produced by one-step single-nozzle electrospinning. Loading different species of active agents in each colloid provides control over the release of each of the agents independently, which enables a programmed release pattern for multiple agents.