4.8 Article

Favorable Modulation of Pre-Osteoblast Response to Nanograined/Ultrafine-grained Structures in Austenitic Stainless Steel

期刊

ADVANCED MATERIALS
卷 21, 期 12, 页码 1280-+

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WILEY-V C H VERLAG GMBH
DOI: 10.1002/adma.200802478

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资金

  1. National Science Foundation, USA [0757799]
  2. Directorate For Engineering
  3. Div Of Civil, Mechanical, & Manufact Inn [0757799] Funding Source: National Science Foundation

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Nanograined (NG)/ultrafine-grained (UFG) structures show enhanced cellular response of pre-osteoblasts. Cell proliferation, viability, and morphology on phase-reversion annealed NG/UFG austenitic stainless steel were observed to be favorably modulated in comparison to conventional coarse-grained austenitic stainless steel. The improvement in cellular response is ascribed to NG/UFG structure and hydrophilicity of the cell substrate.

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