期刊
ADVANCED MATERIALS
卷 20, 期 9, 页码 1630-+出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/adma.200800004
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- NCI NIH HHS [R01 CA124427, R01 CA124427-01, U54 CA119335, U54 CA119335-01] Funding Source: Medline
The synthesis, in vitro, and in vivo The particles consist of a chainlike aggregation of iron oxide (IO) cores in a dextran coating. When conjugated with a tumor-targeting peptide, they interact more effectively with a tumor-based target in vitro relative to spherical nanoparticles. Untargeted NW display similar in vivo circulation times and enhanced passive accumulation in mouse xenograft tumors relative to untargeted spherical IO nanoparticles.
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