Laterally spaced linear nanoparticle arrays templated by laminated β-sheet fibrils

Parallel, linear gold nanoparticle arrays with a periodic lateral spacing have been created via templated assembly. The template is a de novo designed peptide that self-assembles into beta-sheet fibrils exhibiting a laminated morphology. Regular arrangement of positively charged lysine residues across the width of the fibril and complementary electrostatic interactions with negatively charged gold nanoparticles directs the particles into linear arrays (see figure).