期刊
ADVANCED FUNCTIONAL MATERIALS
卷 28, 期 40, 页码 -出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/adfm.201802140
关键词
antibacterial polymers; cell proliferation; coagulation; hemocompatibility; kill-and-release
类别
资金
- National Key Research and Development Program of China [2016YFC1100404]
- National Natural Science Foundation of China [21504006, 51573014, 51733001]
- Beijing Municipal Natural Science Foundation [L160004, 7161001]
- Eastern Scholar Professorship from Shanghai local government [TP2014034]
Antibacterial materials that prevent bacterial infections and mitigate bacterial virulence have attracted great scientific interests. In recent decades, the bactericidal polymers have been presented as promising candidates to combat bacterial pathogens, mainly based on the construction of bactericidal cationic polymers, functionalization with biocidal agents, and formation of bacterial-repelling layers. However, these established strategies have inherent disadvantages because they often overlook important features such as their biocompatibility and biosafety, especially for biomedical applications. In recent years, many efforts have been made focusing on the development of multifunctional antibacterial materials to meet the elaborate requirements for medical devices and public hygiene products. Herein the recent advances in developing multifunctional materials for their antibacterial activities together with other functions including kill-and-release capability, hemocompatibility, cell proliferation promoting properties, and coagulation promoting ability for wound dressing are highlighted. In addition, the outlooks on the remaining challenges that should be addressed in the field of multifunctional antibacterial materials are also described.
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