期刊
ADVANCED DRUG DELIVERY REVIEWS
卷 65, 期 1, 页码 104-120出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.addr.2012.10.003
关键词
Commercialized drug delivery system; Nanoparticle; Polyplex; Natural polymers; Polymer-drug conjugate; Combinatorial chemistry; Microfluidics; Particle replication in non-wetting template; Step-flash imprint lithography
资金
- NSF [EEC-0425626]
- NIH [HL089764, HL109442]
- Agency for Science, Technology and Research (Singapore)
- Sir Edward Youde Memorial Fund Council (Hong Kong)
- NATIONAL HEART, LUNG, AND BLOOD INSTITUTE [R01HL089764, R01HL109442] Funding Source: NIH RePORTER
- NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES [R01AI096305] Funding Source: NIH RePORTER
- NATIONAL INSTITUTE OF BIOMEDICAL IMAGING AND BIOENGINEERING [R21EB015300] Funding Source: NIH RePORTER
Design and synthesis of efficient drug delivery systems are of vital importance for medicine and healthcare. Materials innovation and nanotechnology have synergistically fueled the advancement of drug delivery. Innovation in material chemistry allows the generation of biodegradable, biocompatible, environment-responsive, and targeted delivery systems. Nanotechnology enables control over size, shape and multi-functionality of particulate drug delivery systems. In this review, we focus on the materials innovation and processing of drug delivery systems and how these advances have shaped the past and may influence the future of drug delivery. (C) 2012 Elsevier B.V. All rights reserved.
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