期刊
ADVANCED DRUG DELIVERY REVIEWS
卷 65, 期 15, 页码 2045-2060出版社
ELSEVIER
DOI: 10.1016/j.addr.2013.08.001
关键词
Photothermal therapy; Carbon nanotubes; Single-walled nanotubes; Multiwalled nanotubes; Cancer therapy
资金
- National Cancer Institute/National Institutes of Health [RO1CAl2842, R00CA154006]
- Department of Defense [W81XWH-10-1-0434]
Thermal tumor ablation therapies are being developed with a variety of nanomaterials, including single- and multiwalled carbon nanotubes. Carbon nanotubes (CNTs) have attracted interest due to their potential for simultaneous imaging and therapy. In this review, we highlight in vivo applications of carbon nanotube-mediated thermal therapy (CNMTT) and examine the rationale for use of this treatment in recurrent tumors or those resistant to conventional cancer therapies. Additionally, we discuss strategies to localize and enhance the cancer selectivity of this treatment and briefly examine issues relating the toxicity and long term fate of CNTs. (C) 2013 Elsevier B.V. All rights reserved.
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