期刊
ADVANCED DRUG DELIVERY REVIEWS
卷 65, 期 2, 页码 169-190出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.addr.2012.04.009
关键词
Percutaneous drug delivery; Mathematical modelling
资金
- National Health & Medical Research Council of Australia
- Australian Research Council
Topical delivery to the various regions of the skin and underlying tissues, transdermal drug delivery and dermal exposure to environmental chemicals are important areas of research. Mathematical models of epidermal and dermal transport, involving penetration of a solute through various layers of the skin, metabolism in the skin and its subsequent distribution and clearance into systemic circulation from underlying tissues, play an essential role in this research area and are reviewed in this work. (C) 2012 Elsevier B.V. All rights reserved.
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