期刊
ADVANCED DRUG DELIVERY REVIEWS
卷 64, 期 15, 页码 1800-1819出版社
ELSEVIER
DOI: 10.1016/j.addr.2012.05.008
关键词
Silicon; Silica; Nanomaterials; Biocompatibility; Toxicity; Mesoporous
资金
- Susan G. Komen Postdoctoral Fellowship [PDF12229449]
- NIH [U54CA143837, 1U54CA151668-01]
- DOD [W81XWH-09-1-0212, W81XWH-11-02-0168]
Silicon is one of the most abundant chemical elements found on the Earth. Due to its unique chemical and physical properties, silicon based materials and their oxides (e.g. silica) have been used in several industries such as building and construction, electronics, food industry, consumer products and biomedical engineering/medicine. This review summarizes studies on effects of silicon and silica nano- and micro-particles on cells and organs following four main exposure routes, namely, intravenous, pulmonary, dermal and oral. Further, possible genotoxic effects of silica based nanoparticles are discussed. The review concludes with an outlook on improving and standardizing biocompatibility assessment for nano- and micro-particles. (C) 2012 Elsevier B.V. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据