期刊
ADVANCED DRUG DELIVERY REVIEWS
卷 64, 期 15, 页码 1663-1693出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.addr.2012.05.014
关键词
Nanomaterials; Nanoparticles; Nanodescriptors; Quantum-chemical methods; Nano-QSAR; Toxicity
资金
- NSF CREST Interdisciplinary Nanotoxicity Center NSF-CREST [HRD-0833178]
- NSF-EPSCoR [362492-190200-01\NSFEPS-0903787]
- Department of Defense through the U. S. Army Engineer Research and Development Center, Vicksburg, MS [W912HZ-06-C-0057]
- 711 HPW/RHP [FA8650-10-2-6062]
- Foundation for Polish Science
- Polish Ministry of Science and Higher Education [DS/8180-4-0171-12]
- European Social Fund
- State Budget and the Pomorskie Voivodeship Budget according to the Operational Programme Human Capital, Priority VIII, Action 8.2, Under-action 8.22: 'Regional Innovation Strategy'
- Division Of Human Resource Development
- Direct For Education and Human Resources [833178] Funding Source: National Science Foundation
- Office Of The Director
- EPSCoR [1006983] Funding Source: National Science Foundation
- Office Of The Director
- EPSCoR [903787] Funding Source: National Science Foundation
Nanotechnology that develops novel materials at size of 100 nm or less has become one of the most promising areas of human endeavor. Because of their intrinsic properties, nanoparticles are commonly employed in electronics, photovoltaic, catalysis, environmental and space engineering, cosmetic industry and - finally - in medicine and pharmacy. In that sense, nanotechnology creates great opportunities for the progress of modem medicine. However, recent studies have shown evident toxicity of some nanoparticles to living organisms (toxicity), and their potentially negative impact on environmental ecosystems (ecotoxicity). Lack of available data and low adequacy of experimental protocols prevent comprehensive risk assessment The purpose of this review is to present the current state of knowledge related to the risks of the engineered nanoparticles and to assess the potential of efficient expansion and development of new approaches, which are offered by application of theoretical and computational methods, applicable for evaluation of nanomaterials. (C) 2012 Elsevier B.V. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据