期刊
ADSORPTION-JOURNAL OF THE INTERNATIONAL ADSORPTION SOCIETY
卷 19, 期 2-4, 页码 269-272出版社
SPRINGER
DOI: 10.1007/s10450-012-9449-4
关键词
Drug delivery; Paracetamol; Nanotubes; Hot melt drug deposition
资金
- NSC [DEC-2011/01/B/ST5/01192]
We discuss the factors influencing the properties of new drug delivery system, composed of carbon nanotubes and analgesic antipyretic drug-paracetamol. Basing on experimental data it is shown, that by a simple manipulation with the heating time at the stage of system preparation, one can easily change the rate of the drug delivery. Moreover, this rate can be changed in a very wide range. Finally, using Molecular Dynamics simulation we also discuss the orientation and properties of drug molecules at different stages of the hot melt deposition process.
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