期刊
ADDICTION BIOLOGY
卷 17, 期 6, 页码 977-980出版社
WILEY
DOI: 10.1111/j.1369-1600.2010.00250.x
关键词
Anterior cingulate; gray matter volume; magnetic resonance imaging; medial frontal cortex; smoking thalamus
资金
- National Key Technology R&D Program of China [2007BAI07B01]
- Natural Science Foundation of China (NSFC) [30971050, 30900486]
- National Key Basic Research and Development Program (NKBRDP) (973) [2006CB500808, 2007CB512301, 2009CB522000]
Magnetic resonance imaging (MRI) studies showed a link between chronic smoking and structural brain abnormalities. To date, little is known about the long-term effects of smoking on gray matter deficiencies. MRI study was carried for 44 smokers and 44 matched non-smokers to assess gray matter volume differences between the two groups. Decreased gray matter volumes were found in left thalamus, medial frontal cortex and anterior cingulate of smokers in comparison to controls. This voxel-based morphometry study is showing reduction of regional gray matter volume in smokers, which might better guide future research into the pathogenesis of chronic smoking.
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