期刊
ACTA TROPICA
卷 115, 期 1-2, 页码 28-34出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.actatropica.2009.12.006
关键词
Protozoa; American trypanosomiasis; Chagas disease; Blood transfusion; Pathogen reduction; Transfusional risk; Leukofiltration
Transfusion transmitted Chagas disease was recognized as a medical problem more than 50 years ago. However, little attention was paid to it by Transfusion Medicine, medical authorities or regulatory agencies as a major problem and threat (especially after the advent of HIV/AIDS): perhaps because it was mainly restricted to tropical regions, usually in less developed countries. With the intense human migratory movement from developing to developed countries, it became more common and evident. The scope of this review is to cover the main transfusional aspects of American trypanosomiasis (Chagas disease), including the main strategies to prevent it through donor questionnaires, specific serological testing and alternative methods such as leukofiltration and pathogen reduction procedures, in order to increase the blood safety in both developing and developed countries. (C) 2009 Elsevier B.V. All rights reserved.
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