期刊
INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY
卷 66, 期 -, 页码 110-118出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.ibmb.2015.10.010
关键词
Aversive behavior; Electrophysiology; GR33a; GR66a; GR93a
资金
- National Research Foundation of Korea (NRF) - Ministry of Science, ICT & Future Planning [2012M3A9B2052525]
- Basic Science Research Program of the NRF of Korea - Ministry of Education [2012R1A1A2003727]
- Kookmin University in Korea [J2013-0027]
- National Research Foundation of Korea [2012R1A1A2003727, 2012M3A9B2052525] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
Studies of taste modality using the animal model Drosophila melanogaster have elucidated a number of uncharacterized mechanisms of sensory responses. Gustatory receptors expressed in taste organs are not only responsible for the acceptance and rejection of different foods, but are also involved in the process of selecting an oviposition site. This contact-chemosensation is essential for animals to discriminate between nutritious and contaminated foods. In this study, we characterized the function of gustatory receptors that play a dual role in feeding and oviposition using the plant metabolite umbelliferone. The combined electrophysiological and behavioral evidence demonstrated that two broadly tuned gustatory receptors, GR33a and GR66a, and one narrowly tuned gustatory receptor, GR93a, are all required to generate a functional umbelliferone receptor. (C) 2015 Elsevier Ltd. All rights reserved.
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