期刊
ACTA RADIOLOGICA
卷 52, 期 3, 页码 336-339出版社
ROYAL SOC MEDICINE PRESS LTD
DOI: 10.1258/ar.2010.100355
关键词
CNS; MR imaging; brain/brainstem; adults
Creutzfeldt-Jakob disease is a rare and fatal neurodegenerative disorder with MR findings predominantly limited to the grey matter of the cortex and the basal ganglia. Sporadic Creutzfeldt-Jakob disease can produce a spectrum of MR imaging findings of the brain, most notably on DWI and FLAIR sequences. Involvement of the basal ganglia and neocortex is the most common finding, but isolated involvement of the cortex can also be seen. We describe the clinical history and MRI findings of three patients with sporadic Creutzfeldt-Jakob disease confirmed by brain biopsy or autopsy and review the literature of imaging manifestations of this disease.
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