期刊
ACTA RADIOLOGICA
卷 52, 期 2, 页码 211-222出版社
SAGE PUBLICATIONS LTD
DOI: 10.1258/ar.2010.100053
关键词
Neuroimaging biomarkers; Alzheimer's disease; magnetic resonance imaging; voxel-based morphometry; functional MRI; functional connectivity MRI; diffusion tensor imaging; arterial spin labeling; magnetic resonance spectroscopy
The aim of this review is to examine the recent literature on using advanced magnetic resonance imaging (MRI) techniques for finding neuroimaging biomarkers that are sensitive to the detection of risks for Alzheimer's disease (AD). Since structural MRI techniques, such as brain structural volumetry and voxel-based morphometry (VBM), have been widely used for AD studies and extensively reviewed, we will only briefly touch on the topics of volumetry and morphometry. The focus of the current review is about the more recent developments in the search for AD neuroimaging biomarkers with functional MRI (fMRI), resting-state functional connectivity MRI (fcMRI), diffusion tensor imaging (DTI), arterial spin-labeling (ASL), and magnetic resonance spectroscopy (MRS).
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