4.5 Article

Rhabdomyolysis and brain ischemic stroke in a heroin-dependent male under methadone maintenance therapy

期刊

ACTA PSYCHIATRICA SCANDINAVICA
卷 120, 期 1, 页码 76-79

出版社

WILEY
DOI: 10.1111/j.1600-0447.2009.01378.x

关键词

heroin; ischemia; stroke; rhabdomyolysis; methadone

向作者/读者索取更多资源

Objective: There are several complications associated with heroin abuse, some of which are life-threatening. Methadone may aggravate this problem. Method: A clinical case description. Results: A 33-year-old man presented with rhabdomyolysis and cerebral ischemic stroke after intravenous heroin. He had used heroin since age 20, and had used 150 mg methadone daily for 6 months. He was found unconsciousness at home and was sent to our hospital. In the ER, his opiate level was 4497 ng/ml. In the ICU, we found rhabdomyolysis, acute renal failure and acute respiratory failure. After transfer to an internal ward, we noted aphasia and weakness of his left limbs. After MRI, we found cerebral ischemic infarction. Conclusion: Those using methadone and heroin simultaneously may increase risk of rhabdomyolysis and ischemic stroke. Patients under methadone maintenance therapy should be warned regarding these serious adverse events. Hypotheses of heroin-related rhabdomyolysis and stroke in heroin abusers are discussed.

作者

我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

4.5
评分不足

次要评分

新颖性
-
重要性
-
科学严谨性
-
评价这篇论文

推荐

暂无数据
暂无数据