期刊
ACTA PHYSIOLOGICA
卷 199, 期 2, 页码 149-160出版社
WILEY
DOI: 10.1111/j.1748-1716.2010.02116.x
关键词
Gi; immunological response; nucleotide; nucleotide sugar; P2Y receptor; UDP
类别
资金
- USPHS [GM38213, HL34322]
The P2Y(14) receptor is a relatively broadly expressed G protein-coupled receptor that is prominently associated with immune and inflammatory cells as well as with many epithelia. This receptor historically was thought to be activated selectively by UDP-glucose and other UDP-sugars. However, UDP is also a very potent agonist of this receptor, and may prove to be one of its most important cognate activators.
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