CURCUMIN THERAPEUTIC PROMISES AND BIOAVAILABILITY IN COLORECTAL CANCER

Curcumin, a polyphenol and derivative of turmeric is one of the most commonly used and highly researched phytochemicals Several research studies have provided interesting insights into the multiple mechanisms by which curcumin may mediate chemotherapy and chemopreventive effects on cancers, including colorectal cancer Curcumin has the ability to inhibit carcinogenic promotion of colorectal cancer through the modulation of multiple molecular targets such os transcription factors, enzymes, cell cycle proteins, cell surface adhesion proteins, survival pathways and cytokines A number of clinical trials dealing