4.7 Article

Geographic Differences in Genetic Locus Linkages for Borrelia burgdorferi

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EMERGING INFECTIOUS DISEASES
卷 16, 期 7, 页码 1147-1150

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CENTERS DISEASE CONTROL
DOI: 10.3201/eid1607.091452

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  1. Centers for Disease Control and Prevention Cooperative Agreement [CI 00171-01]
  2. National Institutes of Health [AI065359]

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Borrelia burdorferi genotype in the northeastern United States is associated with Lyme borreliosis severity. Analysis of DNA sequences of the outer surface protein C gene and rrs-rrlA intergenic spacer from extracts of Ixodes spp. ticks in 3 US regions showed linkage disequilibrium between the 2 loci within a region but not consistently between regions.

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