The Oncomouse That Roared: Hybrid Exchange Strategies as a Source of Distinction at the Boundary of Overlapping Institutions

Conventional wisdom suggests that when institutional logics overlap, the production of hybrids signifies collapse, blending, or easy coexistence. The author provides an alternative interpretation: hybrids can maintain a distinctive boundary and can emerge from contestation, not coexistence. This alternative interpretation is grounded in an analysis of a critical moment at the academic-commercial boundary: the enforcement of patents to a key technology on academic geneticists. In their reaction to commercial encroachment, skilled actors (scientists) took the resources of the commercial logic and transformed their meaning to establish hybrid strategies that preserved the distinctive institutions. Thus, hybrids must be reconsidered as emerging from conflict and produced through boundary work to maintain the distinction and resilience of logics.