期刊
ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA
卷 93, 期 12, 页码 1262-1267出版社
WILEY
DOI: 10.1111/aogs.12490
关键词
Bowel endometriosis; resection margins; segmental resection; recurrence
资金
- University Hospital of Berne
ObjectiveTo evaluate possible predictive factors for recurrence after laparoscopic segmental bowel resection for bowel endometriosis. DesignCohort study. SettingAcademic tertiary referral center. Methods95 symptomatic women with bowel endometriosis who underwent laparoscopic segmental bowel resection at the Endometriosis clinic, University of Berne, between 2002 and 2012 were enrolled. Since 14 women were lost to follow-up, 81 formed the final cohort. Clinical and histological characteristics were examined as possible predictive factors for disease recurrence. Main outcome measuresRecurrence, defined as a subsequent operation due to recurrent endometriosis-associated pain with a histologically confirmed endometriotic lesion. ResultsRecurrence was observed in 13 (16%) patients. Variables that were significantly associated to recurrence by the Cox regression analysis were positive bowel resection margins (hazard ratio 6.5, 95% confidence interval 1.8-23.5, p=0.005), age <31years (hazard ratio 5.6, 95% confidence interval 1.7-18.6, p=0.005) and body mass index 23kg/m(2) (hazard ratio 11.0, 95% confidence interval 2.7-44.6, p=0.001). ConclusionsPositive bowel resection margins as well as age <31years and body mass index 23kg/m(2) appear to be independent predictors of disease recurrence.
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