相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Amyloid-β42 alters apolipoprotein E solubility in brains of mice with five familial AD mutations
Katherine Lynn Youmans et al.
JOURNAL OF NEUROSCIENCE METHODS (2011)
Reduced levels of human apoE4 protein in an animal model of cognitive impairment
P. M. Sullivan et al.
NEUROBIOLOGY OF AGING (2011)
Plasma apolipoprotein E and Alzheimer disease risk The AIBL study of aging
V. B. Gupta et al.
NEUROLOGY (2011)
Human apoE Isoforms Differentially Regulate Brain Amyloid-β Peptide Clearance
Joseph M. Castellano et al.
SCIENCE TRANSLATIONAL MEDICINE (2011)
Accumulation of intraneuronal Aβ correlates with ApoE4 genotype
Ditte Z. Christensen et al.
ACTA NEUROPATHOLOGICA (2010)
Capillary cerebral amyloid angiopathy identifies a distinct APOE ε4-associated subtype of sporadic Alzheimer's disease
Dietmar Rudolf Thal et al.
ACTA NEUROPATHOLOGICA (2010)
The role of ATP-binding cassette transporter A1 in Alzheimer's disease and neurodegeneration
Radosveta Koldamova et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2010)
ATP-binding Cassette Transporter A1 Mediates the Beneficial Effects of the Liver X Receptor Agonist GW3965 on Object Recognition Memory and Amyloid Burden in Amyloid Precursor Protein/Presenilin 1 Mice
James J. Donkin et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Liver X Receptor Agonist Treatment Ameliorates Amyloid Pathology and Memory Deficits Caused by High-Fat Diet in APP23 Mice
Nicholas F. Fitz et al.
JOURNAL OF NEUROSCIENCE (2010)
THE EFFECT OF APOE GENOTYPE ON BRAIN LEVELS OF OXYSTEROLS IN YOUNG AND OLD HUMAN APOE ε2, ε3 AND ε4 KNOCK-IN MICE
A. M. Jenner et al.
NEUROSCIENCE (2010)
PROGRESSIVE LOSS OF SYNAPTIC INTEGRITY IN HUMAN APOLIPOPROTEIN E4 TARGETED REPLACEMENT MICE AND ATTENUATION BY APOLIPOPROTEIN E2
R. C. Klein et al.
NEUROSCIENCE (2010)
Decreased Clearance of CNS β-Amyloid in Alzheimer's Disease
Kwasi G. Mawuenyega et al.
SCIENCE (2010)
APOE and cholesterol homeostasis in Alzheimer's disease
Valerie Leduc et al.
TRENDS IN MOLECULAR MEDICINE (2010)
The Neuropathology of Probable Alzheimer Disease and Mild Cognitive Impairment
Julie A. Schneider et al.
ANNALS OF NEUROLOGY (2009)
ApoE4 Decreases Spine Density and Dendritic Complexity in Cortical Neurons In Vivo
Sonya B. Dumanis et al.
JOURNAL OF NEUROSCIENCE (2009)
Human APOE Isoform-Dependent Effects on Brain β-Amyloid Levels in PDAPP Transgenic Mice
Kelly R. Bales et al.
JOURNAL OF NEUROSCIENCE (2009)
Clearance mechanisms of Alzheimer's amyloid-beta peptide: implications for therapeutic design and diagnostic tests
K. A. Bates et al.
MOLECULAR PSYCHIATRY (2009)
Apolipoprotein E and its receptors in Alzheimer's disease: pathways, pathogenesis and therapy
Guojun Bu
NATURE REVIEWS NEUROSCIENCE (2009)
A transgenic rat model of Alzheimer's disease with extracellular Aβ deposition
Dorothy G. Flood et al.
NEUROBIOLOGY OF AGING (2009)
The Role of Apolipoprotein E in Alzheimer's Disease
Jungsu Kim et al.
NEURON (2009)
Fibrillar amyloid-β burden in cognitively normal people at 3 levels of genetic risk for Alzheimer's disease
Eric M. Reiman et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Co-localization of amyloid beta and tau pathology in Alzheimer's disease synaptosomes
Jeffrey A. Fein et al.
AMERICAN JOURNAL OF PATHOLOGY (2008)
Middle-aged human apoE4 targeted-replacement mice show retention deficits on a wide range of spatial memory tasks
Alexandra Bour et al.
BEHAVIOURAL BRAIN RESEARCH (2008)
Soluble oligomers of the amyloid β-protein impair synaptic plasticity and behavior
Dennis J. Selkoe
BEHAVIOURAL BRAIN RESEARCH (2008)
apoE isoform-specific disruption of amyloid β peptide clearance from mouse brain
Rashid Deane et al.
JOURNAL OF CLINICAL INVESTIGATION (2008)
Impact of Apolipoprotein E (ApoE) Polymorphism on Brain ApoE Levels
David R. Riddell et al.
JOURNAL OF NEUROSCIENCE (2008)
Human Apolipoprotein E4 Targeted Replacement Mice Show Increased Prevalence of Intracerebral Hemorrhage Associated with Vascular Amyloid Deposition
Patrick M. Sullivan et al.
Journal of Stroke & Cerebrovascular Diseases (2008)
A rapid Percoll gradient procedure for preparation of synaptosomes
Peter R. Dunkley et al.
NATURE PROTOCOLS (2008)
ApoE promotes the proteolytic degradation of Aβ
Qingguang Jiang et al.
NEURON (2008)
Cerebral clearance of human amyloid-β peptide (1-40) across the blood-brain barrier is reduced by self-aggregation and formation of low-density lipoprotein receptor-related protein-1 ligand complexes
Shingo Ito et al.
JOURNAL OF NEUROCHEMISTRY (2007)
Role of gangliosides in Alzheimer's disease
Katsuhiko Yanagisawa
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2007)
Transport pathways for clearance of human Alzheimer's amyloid β-peptide and apolipoproteins E and J in the mouse central nervous system
Robert D. Bell et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2007)
Increased cholesterol in A beta-positive nerve terminals from Alzheimer's disease cortex
Karen Hoppens Gylys et al.
NEUROBIOLOGY OF AGING (2007)
Premorbid effects of APOE on synaptic proteins in human temporal neocortex
Seth Love et al.
NEUROBIOLOGY OF AGING (2006)
Profile and regulation of apolipoprotein E (ApoE) expression in the CNS in mice with targeting of green fluorescent protein gene to the ApoE locus
Qin Xu et al.
JOURNAL OF NEUROSCIENCE (2006)
Apolipoprotein E4: A causative factor and therapeutic target in neuropathology including Alzheimer's disease
RW Mahley et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
The absence of ABCA1 decreases soluble ApoE levels but does not diminish amyloid deposition in two murine models of Alzheimer disease
V Hirsch-Reinshagen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Lack of ABCA1 considerably decreases brain ApoE level and increases amyloid deposition in APP23 mice
R Koldamova et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Deletion of Abca1 increases Aβ deposition in the PDAPP transgenic mouse model of Alzheimer disease
SE Wahrle et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Effect of domain interaction on apolipoprotein E levels in mouse brain
G Ramaswamy et al.
JOURNAL OF NEUROSCIENCE (2005)
Apolipoprotein E co-localizes with newly formed amyloid β-protein (Aβ) deposits lacking immunoreactivity against N-terminal epitopes of Aβ in a genotype-dependent manner
DR Thal et al.
ACTA NEUROPATHOLOGICA (2005)
Regulation of hippocampal cholesterol metabolism by apoE and environmental stimulation
O Levi et al.
JOURNAL OF NEUROCHEMISTRY (2005)
Apolipoprotein E4 is probably responsible for the chromosome 19 linkage peak for Parkinson's disease
M Martinez et al.
AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS (2005)
Murine synaptosomal lipid raft protein and lipid composition are altered by expression of human apoE 3 and 4 and by increasing age
U Igbavboa et al.
JOURNAL OF THE NEUROLOGICAL SCIENCES (2005)
Human apoE4-targeted replacement mice display synaptic deficits in the absence of neuropathology
CS Wang et al.
NEUROBIOLOGY OF DISEASE (2005)
Applipoprotein E ε4 is a determinant for Alzheimer-type pathologic features in tauopathies, synucleinopathies, and frontotemporal degeneration
KA Josephs et al.
ARCHIVES OF NEUROLOGY (2004)
Enrichment of presynaptic and postsynaptic markers by size-based gating analysis of synaptosome preparations from rat and human cortex
KH Gylys et al.
CYTOMETRY PART A (2004)
Impact of APOE genotype on neuropathologic and neurochemical markers of Alzheimer disease
P Tiraboschi et al.
NEUROLOGY (2004)
Marked regional differences of brain human apolipoprotein E expression in targeted replacement mice
PM Sullivan et al.
NEUROSCIENCE (2004)
Synaptic changes in Alzheimer's disease -: Increased amyloid-β and gliosis in surviving terminals is accompanied by decreased PSD-95 fluorescence
KH Gylys et al.
AMERICAN JOURNAL OF PATHOLOGY (2004)
The ACAT inhibitor CP-113,818 markedly reduces amyloid pathology in a mouse model of Alzheimer's disease
B Hutter-Paier et al.
NEURON (2004)
ApoE and A beta 1-42 interactions
AM Manelli et al.
JOURNAL OF MOLECULAR NEUROSCIENCE (2004)
Triple-transgenic model of Alzheimer's disease with plaques and tangles:: Intracellular Aβ and synaptic dysfunction
S Oddo et al.
NEURON (2003)
Apolipoprotein E enhances uptake of soluble but not aggregated amyloid-β protein into synaptic terminals
KH Gylys et al.
JOURNAL OF NEUROCHEMISTRY (2003)
Apolipoprotein E isoform-specific regulation of dendritic spine morphology in apolipoprotein E transgenic mice and Alzheimer's disease patients
Y Ji et al.
NEUROSCIENCE (2003)
Control of synapse number by glia
EM Ullian et al.
SCIENCE (2001)
Correlation between elevated levels of amyloid β-peptide in the brain and cognitive decline
J Näslund et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2000)