期刊
ACTA NEUROLOGICA SCANDINAVICA
卷 118, 期 6, 页码 387-394出版社
WILEY
DOI: 10.1111/j.1600-0404.2008.01065.x
关键词
activities of daily living; deep brain stimulation; essential tremor; health-related quality of life
资金
- Swedish Brain foundation (Hjarnfonden)
- Vasterbotten County Council (Vasterbottens lans landsting), Sweden
- Research foundation of the Department of Clinical Neuroscience at Umea University, Umea, Sweden
To report long-term effects of thalamic deep brain stimulation (DBS) on activities of daily living (ADL) and health-related quality of life (HRQoL) in patients with essential tremor (ET). Nineteen consecutive patients were evaluated at baseline, at a mean of 1 year, then at a mean of 7 years after DBS using Tremor Rating Scale, Mini Mental Test, ADL Taxonomy, Nottingham Health Profile, Life Satisfaction Checklist, Visual Analogue Scale and interview. There was a decrease of DBS efficacy on tremor between 1 and 7 years post-operatively. The marked improvement in ADL at 1 year was no longer sustained at long-term, except for the ability to eat. Social life remained improved. Although there is a decrease of DBS effect on tremor at 7 years, and even though further ageing and co-morbidities may impact on the well-being of patients, there is still relevant benefit of DBS on few aspects of ADL and HRQoL in patients with ET.
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