期刊
ACTA CYTOLOGICA
卷 52, 期 5, 页码 575-578出版社
SCI PRINTERS & PUBL INC
DOI: 10.1159/000325600
关键词
cervical screening; cytology, automated; Cytyc imager; ThinPrep
类别
Objective To compare agreement of pathologists and cytotechnologists and technologist productivity before and after implementation of the Cytyc ThinPrep Imager. Study Design Using the Cytyc ThinPrep Imaging System, a retrospective analysis was conducted, from the first 6 months in 2004 and in 2005. Total cases in January through June were 79,791 in 2004 and 76,887 in 2005. Data on the number and type of changes from one impression to another were collected in a confusion matrix. The X-2 test with 1 degree of freedom was used to calculate the significance of the difference between the groups. Results Changes in diagnosis were most frequently seen in negative for intraepithelial lesion, atypical squamous cells of undetermined significance and low-grade squamous intraepithelial lesion. Interobserver agreement before the imager (weighted kappa) was 0.74 and after was 0.73. Conclusion The number of high-grade lesions detected increased with the imager (p < 0.01). Technologist productivity increased by an average of 2.2 slides/hour.
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